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Freddy Radtke Selected Research

Adenoma (Adenomas)

6/2005Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells.

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Freddy Radtke Research Topics

Disease

12Neoplasms (Cancer)
01/2020 - 03/2004
3Leukemia
01/2022 - 08/2015
3Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL)
01/2022 - 11/2010
3Alagille Syndrome (Alagille-Watson Syndrome)
12/2012 - 08/2008
3Carcinogenesis
10/2012 - 03/2003
2Graft vs Host Disease (Graft-Versus-Host Disease)
01/2020 - 04/2017
2Melanoma (Melanoma, Malignant)
01/2018 - 11/2016
2Inflammation (Inflammations)
01/2016 - 10/2012
2Blindness (Hysterical Blindness)
06/2014 - 08/2007
2Alzheimer Disease (Alzheimer's Disease)
01/2013 - 06/2005
2Metabolic Bone Diseases (Osteopenia)
02/2010 - 08/2008
1Lymphopenia (Lymphocytopenia)
01/2022
1Adenocarcinoma of Lung
01/2021
1Disease Progression
01/2021
1Lung Neoplasms (Lung Cancer)
01/2021
1B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
01/2021
1Colonic Neoplasms (Colon Cancer)
01/2020
1Colorectal Neoplasms (Colorectal Cancer)
01/2020
1Bites and Stings (Sting)
01/2017
1Atherosclerosis
01/2016
1T-Cell Leukemia (Leukemia, T Cell)
08/2015
1Fibrosis (Cirrhosis)
08/2014
1Hypertrophy
08/2014
1Neoplasm Metastasis (Metastasis)
08/2014
1Hypoxia (Hypoxemia)
08/2014
1Inborn Genetic Diseases (Disease, Hereditary)
12/2012
1Tetralogy of Fallot (Fallot Tetralogy)
12/2012
1Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
04/2012
1Vascular Remodeling
04/2012
1Neointima
09/2011
1Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
11/2010
1Pancreatic Neoplasms (Pancreatic Cancer)
07/2010
1Lichen Planus (Lichen Ruber Planus)
02/2010
1Psoriasis (Pustulosis Palmaris et Plantaris)
02/2010
1Retinal Degeneration
12/2009
1Vascular System Injuries
05/2009
1Pancreatitis
02/2008
1Ischemia
01/2007
1Adenoma (Adenomas)
06/2005

Drug/Important Bio-Agent (IBA)

7LigandsIBA
01/2022 - 08/2008
6Notch ReceptorsIBA
12/2012 - 03/2003
4Proteins (Proteins, Gene)FDA Link
07/2013 - 03/2005
4Amyloid Precursor Protein Secretases (beta-Secretase)IBA
01/2013 - 06/2005
2ChromatinIBA
01/2022 - 01/2022
2CytokinesIBA
01/2017 - 10/2012
2Jagged-1 ProteinIBA
12/2012 - 12/2010
1PlasticsIBA
01/2022
1Transcription Factors (Transcription Factor)IBA
01/2022
1Cre recombinaseIBA
01/2021
1Matrix Metalloproteinases (MMPs)IBA
01/2020
1GlycosyltransferasesIBA
01/2020
1Phosphotransferases (Kinase)IBA
01/2018
1AMP-Activated Protein KinasesIBA
01/2018
1DNA (Deoxyribonucleic Acid)IBA
01/2017
1Conditioned Culture MediaIBA
11/2016
1LDL Receptors (LDL Receptor)IBA
01/2016
1MicroRNAs (MicroRNA)IBA
08/2015
1Transforming Growth Factors (Transforming Growth Factor)IBA
08/2014
1Connective Tissue Growth FactorIBA
08/2014
1Chloroquine (Aralen)FDA LinkGeneric
08/2014
1Retinaldehyde (Retinal)IBA
06/2014
1cadherin 5IBA
07/2013
1Amyloid beta-PeptidesIBA
01/2013
1Amyloid (Amyloid Fibrils)IBA
01/2013
1Thymic Stromal LymphopoietinIBA
10/2012
1CateninsIBA
10/2012
1Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
04/2012
1Ikaros Transcription FactorIBA
11/2010
1Granulocyte Colony-Stimulating Factor (G-CSF)IBA
02/2010
1beta CateninIBA
08/2008
1CeruletideIBA
02/2008
1dibenzazepineIBA
02/2008
1Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA
08/2007
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2007
1Transforming Growth Factor beta (TGF-beta)IBA
05/2006
1Gamma Secretase Inhibitors and ModulatorsIBA
06/2005
1Notch1 ReceptorIBA
03/2004

Therapy/Procedure

5Therapeutics
01/2020 - 05/2009
3Drug Therapy (Chemotherapy)
01/2021 - 07/2013
2Bone Marrow Transplantation (Transplantation, Bone Marrow)
01/2020 - 04/2017
1Immunotherapy
01/2020
1Ligation
04/2012